肾上腺素雾化吸入联合普米克令舒治疗急诊小儿喉炎的安全性分析

Analysis on the safety of aerosol inhalation of epinephrine combined with pulmicort in treatment of laryngitis children during medical emergency

目的探讨肾上腺素雾化吸入配合普米克令舒治疗急诊小儿喉炎的临床安全性与临床体征的改善情况,缓解患儿喉梗阻的现象。方法选取2015年2月-2017年2月在该院治疗的110例小儿喉炎患儿进行研究,随机分成观察组和对照组,每组各55例。对照组接受普米克令雾化吸入舒治疗,研究组接受肾上腺素联合普米克令舒雾化吸入治疗,观察两组临床疗效、体征缓解时间、喉梗阻缓解情况。结果研究组临床治疗总有效率94.5%,对照组临床治疗总有效率69.1%,两组治疗总有效率比较差异有统计学意义(P<0.05);研究组患儿在咳嗽消失时间、喉鸣音消失时间、声嘶消失时间、治疗时间、喉梗阻缓解程度上均明显优于对照组(均P<0.05)。结论肾上腺素雾化吸入联合普米克令舒治疗急诊小儿喉炎的临床疗效显著,安全性高。

Objective To explore the clinical safety and improvements of clinical signs of aerosol inhalation of epinephrine combined with pulmicort in treatment of laryngitis children during medical emergency, relieve laryngeal obstruction. Methods From February 2015 to February 2017, 110 children with laryngitis treated in Chengdu Women ＆ Children＇s Central Hospital were selected and randomly divided in- to study group and control group, 55 children in each group. The children in control group were treated by aerosol inhalation of puhnicort, and the children in study group were treated by aerosol inhalation of epinephrine combined with pulmicort. The clinical effec, ts, remission time of signs, and remission degrees of laryngeal obstruction in the two groups were observed. Results The total effective rates of clinical treat- ment in study group and control group were 94. 5% and 69. 1% , respectively, there was statistically significant difference between the two groups （P〈0. 05） . The disappearance time of cough, dry rales, and trachyphonia, treatment time, and the remission degree of laryngeal obstruction in study group were statistically significantly better than those in control group （P〈0. 05） . Conclusion The clinical efficacy and safety of aerosol inhalation of epinephrine combined with pulmicort in treatment of laryngitis children during medical emergency is signifi- cant.