哌拉西林舒巴坦联合左氧氟沙星治疗老年肺炎的疗效及安全性观察

Efficacy and Safety of Piperacillin-sulbactam Combined With Levofloxacin in Treating Senile Pneumonia

目的观察并探讨哌拉西林舒巴坦联合左氧氟沙星治疗老年肺炎的疗效及安全性。方法随机选取2016年7月—2017年6月的60例老年肺炎患者当作研究对象,并应用随机数字表法分为两组,各30例。实验组应用哌拉西林舒巴坦联合左氧氟沙星,对照组单用哌拉西林舒巴坦。结果实验组的治疗总有效率96.67%高于对照组的治疗总有效率73.33%;实验组的不良反应发生率6.67%低于对照组的不良反应发生率23.33%,差异有统计学意义(P<0.05)。结论哌拉西林舒巴坦联合左氧氟沙星治疗老年肺炎,疗效显著,安全性好。

Objective To observe and discuss the curative effect and safety of piperacillin-sulbactam combined with levofloxacin in the treatment of senile pneumonia. Methods A total of 60 elderly pneumonia patients from July 2016 to June 2017 were randomly selected for the study. The patients were divided into two groups （n=30） by random number table. Piperacillin and sulbactam combined with levofloxacin were used in the experimental group and piperacillin and sulbactam in the control group. Results The total effective rate of the experimental group was significantly higher than that of the control group （96.67% vs. 73.33%）. The incidence of adverse reactions in the experimental group was significantly lower than that of the control group （6.67% vs. 23.33%）, the difference was statistically significant Significance （P〈 0.05）. Conclusion Piperacillin-sulbactam combined with levofloxacin in the treatment of senile pneumonia has obvious curative effect and good safety.