无抽搐电休克治疗严重抑郁症的效果及对认知功能的影响

Clinical efficacy of MECT in the treatment of severe depression and its influence on patients' cognitive function

目的了解严重抑郁症患者用MECT(无抽搐电休克)对病情和对认知功能的影响。方法随机抽取2013—2016年收治确诊的严重抑郁症患者100例,分为对照组(常规抑郁症治疗)和观察组(联合MECT)各50例,分析2组治疗效果。结果根据患者症状改善评估疗效,观察组评估无效例数明显低于对照组,组间总有效率差异有统计学意义(P<0.05);治疗后对患者心理状态进行检测,提示观察组汉密尔顿抑郁量表与焦虑量表等评分数据明显优于对照组,组间差异有统计学意义(P<0.05);治疗后对患者认知功能进行检测,提示各个项目观察组患者指标均明显更具优越性,组间差异有统计学意义(P<0.05)。结论对严重抑郁症患者单纯对症治疗不能取得满意效果,联合MECT可有效提高临床效果并改善认知功能。

Objective To investigate the effect of MECT（modified electroconvulsive treatment）on the improvement of the depression disease and the positive effects on cognitive function of patients with severe depression.Methods The data of patients with severe depression diagnosed in our hospital during the period of 2013-2016 were selected as the general data sources,100 cases of patients were randomly selected and grouped according to their treatment,there were 50 cases of patients of each group,the control group（conventional depression treatment）and the observation group（MECT treatment）,after the completion of treatment,the effects of two treatment methods on patients with severe depression were recorded and compared to understand the clinical value of MECT.Results Efficacy was evaluated by symptom improvement of patients,the number of invalid cases of patients of the observation group was significantly lower than that of patients of the control group,there were significant differences in the total effective rate between patients of two groups（P0.05）;After treatment,the patient＇s psychological state was detected,The scores of the Hamilton depression scale and anxiety scale of patients of the observation group were significantly better than those of patients of the control group,and the difference between groups was significant（P0.05）;After treatment,the patient＇s cognitive function was tested,the results showed that indicators of all patients of the observation group were significantly superior,and the difference between groups was statistically significant（P0.05）.Conclusion Single symptomatic treatment for patients with severe depression cannot achieve satisfactory results,the combination of MECT treatment can effectively improve the clinical effect and improve the cognitive function of patients,and it is important to improve the quality of life and return to society of patients,which is worthy of promotion.