带状疱疹后遗神经痛患者用药依从性及影响因素的横断面调查研究

A cross-sectional study on medication compliance and influence factors in patients with postherpetic neuralgia

目的了解带状疱疹后遗神经痛(PHN)患者用药依从性现状及其影响因素。方法采用横断面调查的方法,调查2014年1月至2015年3月就诊于陆军军医大学西南医院疼痛门诊的PHN患者用药依从性现状,采用多因素Logistic回归方法分析用药依从性的影响因素。结果共纳入396例PHN患者,52.3%患者用药依从性良好,47.7%依从性差。单因素分析显示,影响用药依从性的因素为年龄、文化程度、婚姻状况、居住情况、经济状况、疼痛程度、病程、医保报销比例、不良反应及合并其他疾病(P<0.05)。多因素Logistic回归分析结果显示:影响用药依从性的因素为年龄、文化程度、婚姻状况、居住情况、经济状况、疼痛程度、病程、医保报销比例、不良反应、合并其他疾病。结论 PHN患者服药依从性不高,影响患者用药依从性的因素较多,建议开展健康教育、加强患者心理干预和建立随访用药依从性制度以提高用药依从性。

Objective To understand the current status of medication compliance in the patients with postherpetie neuralgia （PHN） and its influencing factors. Methods The cross-sectional survey method was adopted to investigate the status quo of medication compliance among PHN patients in the pain clinic of the Southwest Hospital of Army Military Medical University from January of 2014 to March of 2015. Then the influence factors of medication compliance were analyzed by using the using the Logistic re gression method. Results A total of 396 PHN patients were included 52.3% of patients had good medication compliance,while 47.7 % had poor compliance. The univariate analysis showed that the age, educational level,marital status,living condition, economic status, degree of pain, disease course, medical insurance reimbursement, adverse drug reactions and complicating other diseases were the factors affecting the medication compliance （P〈0.05）. The multivariate Logistic regression analysis results showed that the age, educational level, marital status, living condition, economic status, degree of pain, disease course, medical insurance reimbursement, adverse drug reactions and complicating other diseases were the factors affecting the medication compliance. Conclusion The medication compliance in the patients with PHN is not high, there are many factors affecting the medication compliance. It is recommended to carry out the health education, strengthen the psychological intervention of the patients and establish the follow-up medication compliance system for improving the medication compliance.