脑震荡后综合征MRI研究进展

Research progresses of MRI in postconcussion syndrome

轻度脑外伤(mTBI)是临床常见病,部分患者伤后数月或数年仍存在持久的脑震荡后综合征(PCS)。早期识别高PCS风险患者、评估mTBI伤情及监测预后已成为当代医学的重点难题之一。随着MR性能的不断提高和设备的普及,新技术如弥散峰度成像、动脉自旋标记成像、磁敏感加权成像及静息态功能MRI等可用于分析脑微观结构和功能变化,从而提高对mTBI的认识。本文对PCS的MRI诊断进展进行综述。

Mild traumatic brain injury （mTBI） is a common clinical disease, and some of these patients still have postconcussion syndrome （PCS） for months or years after injury. Currently, the assessment of mTBI, prognosis monitoring and early identification of patients with high risk of PCS after injury have become one of the key problems in contemporary medicine. With the improvement of MR performance and the popularization of equipments, new technologies, such as diffusion kurtosis imaging （DKI）, arterial spin labeling （ASL）, susceptibility weighted imaging （SWI） and resting state function MRI（rs-fMRI）, can be used to analyze microstructure and functional changes of brain, therefore improve the understanding of mTBI to a higher and more comprehensive level. The progresses of MRI in PCS were reviewed in this article.