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全麻与脊椎-硬膜外阻滞麻醉对手术患者术后认知功能的影响分析 被引量:2

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摘要 目的比较全身麻醉(全麻)与脊椎-硬膜外阻滞麻醉对手术患者术后认知功能的影响。方法 66例手术患者,随机分为参照组和实验组,各33例。参照组实行全身麻醉,实验组实行脊椎-硬膜外阻滞麻醉,观察比较两组患者术后认知功能。结果实验组术后认知功能障碍发生例数为1例,术后认知功能障碍发生率为3.03%(1/33),参照组术后认知功能障碍发生例数为8例,术后认知功能障碍发生率为24.24%(8/33),实验组术后认知功能障碍发生率低于参照组,差异具有统计学意义(χ2=6.3041,P=0.0120<0.05)。实验组术前及术后6、24 h简易智力状态检查量表(MMSE)评分分别为(30.21±2.31)、(22.21±3.01)、(26.35±2.04)分,参照组术前及术后6、24 h MMSE评分分别为(30.98±3.05)、(16.24±2.11)、(19.21±1.54)分;两组术前MMSE评分比较差异无统计学意义(t=1.1561,P>0.05);实验组术后6、24 h MMSE评分高于参照组,差异具有统计学意义(t=9.3297、16.0469,P<0.05)。结论将脊椎-硬膜外阻滞麻醉与全身麻醉应用在手术患者中均可获得显著效果,但脊椎-硬膜外阻滞麻醉更值得临床应用。
出处 《中国现代药物应用》 2018年第5期53-55,共3页 Chinese Journal of Modern Drug Application
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