青年脑梗死危险因素分析

Analysis of risk factors for cerebral infarction in young people

目的探讨青年脑梗死的危险因素,为临床制定青年脑梗死防治措施提供参考。方法选取2010年1月至2016年6月河南省荣军医院收治的青年脑梗死患者80例为观察组,并选取同期进行健康体检者80例作为对照组。对2组受试者的临床资料进行单因素和多因素分析。结果单因素分析结果显示,高血压、使用降压药、糖尿病、口服降糖药、使用胰岛素、高胆固醇血症、高三酰甘油血症、低密度脂蛋白水平升高、高密度脂蛋白水平降低、吸烟史、饮酒史、心房颤动史、心肌梗死史与青年脑梗死有关(P<0.05)。Logistic回归分析结果显示,高血压、糖尿病、吸烟史、饮酒史、心房颤动史、高胆固醇血症、低密度脂蛋白水平升高、高密度脂蛋白水平降低及高三酰甘油血症是青年脑梗死的独立危险因素(P<0.05)。结论青年脑梗死发生的危险因素较多,应针对各项危险因素制定有效的防范措施,以降低青年脑梗死发病率。

Objective To investigate the risk factors for cerebral infarction in young people,and to provide reference for making clinical prevention and treatment measures of cerebral infarction in young people. Methods Eighty young patients with cerebral infarction from January 2010 to June 2016 in Henan Rongjun Hospital were selected as the observation group,and eighty healthy people were selected as control group at the same period. The clinical data of the subjects in the two groups were analyzed by univariate and multivariate analysis. Results Univariate analysis showed that hypertension,using antihypertensive drugs,diabetes,peroral hypoglycemic agents,using insulin,hypercholesterolemia,hypertriglyceridemia,high level of low density lipoprotein,low level of high density lipoprotein,smoking history,drinking history,atrial fibrillation history and myocardial infarction history were related to cerebral infarction in young people（ P〈 0. 05）. Logistic regression analysis showed that hypertension,diabetes,smoking history,drinking history,atrial fibrillation history,hypercholesterolemia,low level of high density lipoprotein,high level of low density lipoprotein and hypertriglyceridemia were the independent risk factors for cerebral infarction in young people（ P〈 0. 05）. Conclusion There are many risk factors for cerebral infarction in young people,and the effective prevention measures according to various risk factors should be taken to reduce the incidence of cerebral infarction in young people.