摘要
In the landscape of desirable stem-cell-based regeneration,the fate of cell is directed by orchestrated dialog between nanoscale subcellular receptors and biointerfacial niches^([1]).This bottom-up development manner has inspired a great many nanogeometric^([2])and nanotopographic^([3])material-based biointerfaces promising for regenerative medicine.These previous studies shed
In the landscape of desirable stem-cell-based regenera- tion, the fate of cell is directed by orchestrated dialog between nanoscale subcellular receptors and biointerfa- cial niches [1]. This bottom-up development manner has inspired a great many nanogeometric [2] and nanotopo- graphic [3] material-based biointerfaces promising for regenerative medicine. These previous studies shed light on the critical role of nanoscale cell-surfaces interactions in guiding cell fate, but those biointerfaces with properties static in time often inadequately mimic the active control manner of nature life.