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Biotechnology smart control over stem cell fate commitment at nanoscale

Biotechnology smart control over stem cell fate commitment at nanoscale
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摘要 In the landscape of desirable stem-cell-based regeneration,the fate of cell is directed by orchestrated dialog between nanoscale subcellular receptors and biointerfacial niches^([1]).This bottom-up development manner has inspired a great many nanogeometric^([2])and nanotopographic^([3])material-based biointerfaces promising for regenerative medicine.These previous studies shed In the landscape of desirable stem-cell-based regenera- tion, the fate of cell is directed by orchestrated dialog between nanoscale subcellular receptors and biointerfa- cial niches [1]. This bottom-up development manner has inspired a great many nanogeometric [2] and nanotopo- graphic [3] material-based biointerfaces promising for regenerative medicine. These previous studies shed light on the critical role of nanoscale cell-surfaces interactions in guiding cell fate, but those biointerfaces with properties static in time often inadequately mimic the active control manner of nature life.
作者 Xun Wang
出处 《Science China Materials》 SCIE EI CSCD 2018年第3期435-436,共2页 中国科学(材料科学(英文版)
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