植物中亚精胺类物质的化学结构及生理活性研究进展

Review on Chemical Structures and Biological Activities of Spermidine Derivatives in Plants

亚精胺类物质是亚精胺上氨基或亚氨基上氢原子被不同官能团取代而生成的一系列衍生物,其广泛存在于植物的花粉、叶及果实中。目前已知的亚精胺类物质的种类不多,其分离鉴定,特别是生物活性还有很大的研究空间。本文总结了近30年来从植物中发现的多种亚精胺类物质的相关报道,重点概述了非环状和环状两大类亚精胺类物质的化学结构、来源、分离纯化方法及其表现出的抗抑郁、镇痛和降血压等生物活性,以期为系统研发更多特色亚精胺类物质提供参考。

Spermidine derivatives,which widely existed in the pollen,leaf and fruit in the plants,are a kind of natural compounds which the hydrogen atom of spermidine is replaced by other functional group. The structural identification,purification,especially the biological activities of spermidine derivatives are still worthy to explore. This review summarizes the chemical structures,sources,purification and biological activities of spermidine derivatives reported in the past 30 years,which may possibly build a foundation for future research of spermidine derivatives with special functions.