支气管肺泡灌洗术对改善老年脑梗塞并吸入性肺炎炎性因子水平的影响

Effects of Bronchoalveolar Lavage on the Improvement of The Levels of Inflammatory Factors in Senile Cerebral Infarction and Inhalation Pneumonia

目的:观察老年脑梗塞并吸入性肺炎患者采用支气管肺泡灌洗术的临床效果,探讨其对炎性因子水平的影响。方法:选取医院收治的脑梗塞并吸入性肺炎的老年患者70例,随机分为研究组和对照组,每组各35例。对照组给予常规治疗,研究组在对照组的基础上给予支气管肺泡灌洗术治疗。比较2组患者的治疗前、后炎性因子水平和临床疗效。结果:2组患者治疗后IL-1、IL-6、TNF-α水平均明显下降(P<0.05),其中研究组下降程度明显低于对照组(P<0.05);研究组总有效率明显高于对照组(P<0.05)。结论:老年脑梗塞并吸入性肺炎患者采用支气管肺泡灌洗术的临床效果显著,能有效改善其炎症因子水平,值得临床推广应用。

Objective:To observe the effects of bronchoalveolar lavage on the elderly patients with cerebral infarction and inhalation pneumonia and to investigate the effects on the level of inflammatory factors.Methods:70 cases of senile patients with cerebral infarction and aspiration pneumonia admitted in the People's Hospital of Zhangshu had been randomly divided into the study group and the control group,35 cases in each.The control group had been given routine treatment,the study group with bronchoalveolar lavage combined with routine treatment.The levels of pretherapy and posttherapy inflammatory factors and the clinical efficacy of the 2 groups had been compared.Results:After treatment,the levels of IL-1,IL-6 and TNF-alpha in the 2 groups were significantly decreased(P<0.05),The degree of decline of the study group was significantly lower than that of the control group(P<0.05);The total effective rate of the study group was significantly higher than that of the control group(P<0.05).Conclusion:Bronchoalveolar lavage is effective in elderly patients with cerebral infarction and aspiration pneumonia.It can effectively improve the level of inflammatory factors and is worthy of clinical application.