复方菖蒲益智汤治疗中风后轻度认知功能障碍的临床效果

Clinical effect of compound Changpu Yizhi decoction on mild cognitive impairment after stroke

目的分析复方菖蒲益智汤治疗中风后轻度认知功能障碍的临床疗效。方法选取2015年1月至2017年6月我院收治的中风后轻度认知功能障碍患者76例为观察组,同期选取73例中风后轻度认知功能障碍为对照组,对照组口服尼莫地平片,观察组予复方菖蒲益智汤。分别于治疗前、后采用MMSE量表和Mo CA量表评估两组患者认知功能,采用经颅多普勒仪测定其脑血管血流速度。结果治疗后,两组MMSE评分和Mo CA评分均升高,且观察组均高于对照组(P<0.05)。治疗后,两组双侧ACA、MCA、PCA和VA及BA的血流速度均升高,且观察组均高于对照组(P<0.05)。结论复方菖蒲益智汤可改善中风后轻度认知功能障碍患者的脑血流速度,提高其认知功能,其疗效优于尼莫地平。

Objective To explore the clinical effect of compound Changpu Yizhi decoction on mild cognitive impairment after stroke. Methods From January 2015 to June 2017, 76 cases of patients with mild cognitive impairment after stroke treated in our hospital were selected as the observation group, and 73 cases of patients with mild cognitive impairment after stroke in the same period were selected as the control group. The control group was treated with nimodipine tablets, and the observation group was treated with compound Changpu Yizhi decoction. The MMSE and Mo CA scales were used to assess the cognitive function before and after treatment, and cerebral blood flow velocity was measured by transcranial doppler. Results After treatment, the MMSE score and Mo CA score increased in both groups, and those in the observation group were higher than the control group(P<0.05). After treatment, the blood flow velocity of bilateral ACA, MCA, PCA,VA and BA increased in both groups, and those of the observation group were higher than the control group( P <0.05).Conclusion Compound Changpu Yizhi decoction can improve the cerebral blood flow velocity and the cognitive function of patients with mild cognitive impairment after stroke, and the curative effect is better than nimodipine.