放射性肠炎的发病机制及其治疗进展

The pathogenesis and progress of treatment of radiation enteritis

放射性肠炎(RE)是放疗后常见的肠道并发症,可累及肠道任何节段,临床主要表现为腹痛、腹泻,严重者可发生肠梗阻、肠穿孔以及肠瘘等。本病病理变化特殊,处理困难,主要以预防为主。但对于已经发生RE者,目前主要治疗措施包括药物、高压氧等内科保守方法,缺乏统一的治疗策略。本研究就RE的发病机制、治疗进展作一综述,为RE的临床诊治提供一定参考。

Radiation enteritis(RE) is a common intestinal complication after radiotherapy, and can affect any segment of the intestine. The main clinical manifestations were abdominal pain, diarrhea, and patients with severe illness can produce intestinal obstruction, intestinal perforation and intestinal fistula. The pathological changes of the disease are special,and the treatment is difficult. The main treatment measures include drug, hyperbaric oxygen and other conservative methods of internal medicine for RE, but it is lack of unified strategy. This study makes a review of the pathogenesis and the progress in the treatment of RE. It provides a reference for the diagnosis and treatment of RE.