2013～2015年武汉市34家医院抗高血压药使用情况分析

Analysis on Antihypertensive Drugs Used in 34 Hospitals of Wuhan City during 2013 and 2015

目的:探讨抗高血压药在武汉市的利用情况与发展趋势。方法:对武汉市34家医院2013~2015年抗高血压药的种类、销售金额和用药频度(DDDs)等进行统计和分析。结果:2013~2015年抗高血压药的年度销售总金额逐年增长,分别为20 896.67,23 527.19,24 033.44万元,其中不同类别药物构成比变化不大,钙通道阻滞药(CCB)、血管紧张素Ⅱ受体拮抗药(ARB)、肾上腺素受体阻断药和血管紧张素转化酶抑制药(ACEI)在3年中均居前4位,新型复方制剂的销售金额和DDDs逐年增加。单药品种销售金额和DDDs排名前2位的分别是左旋氨氯地平和氨氯地平。结论:在武汉市,CCB、ARB、ACEI、肾上腺素受体阻断药和利尿药最常用,符合目前高血压治疗用药的指南推荐。

Objective： To investigate the current situation and trend of the utilization of antihypertensive drugs in Wuhan city.Methods： The utilization data including varieties,consumption sum and DDDs of antihypertensive drugs in 34 hospitals in Wuhan city from 2013 to 2015 were analyzed. Results： The annual consumption sum of antihypertensive drugs increased year by year,and the value was 20 896. 67,23 527. 19 and 24 033. 44 million yuan,respectively. The calcium-channel blockers（ CCB）,angiotensin Ⅱ receptor antagonist（ ARB）,adrenergic receptor blockers and angiotensin converting enzyme inhibitors（ ACEIs） ranked the top four in consumption sum of antihypertensive drugs. Their constituent ratio was not changed during 2013 and 2015. The consumption amount and DDDs of new compound preparations increased. Top two drugs in terms of consumption amount and DDDs were amlodipine and levamlodipine. Conclusion： CCB,ARB,ACEI,adrenergic receptor blockers and diuretics occupy the predominant places among all the antihypertensive drugs in Wuhan city,which is accordance with the current treatment guideline of antihypertensive drugs.