两种方法手术治疗增殖型糖尿病视网膜病变的疗效对比观察

Observation of two methods surgical treatment of proliferative diabetic retinopathy

目的探讨两种方法手术治疗增殖型糖尿病视网膜病变的疗效,为两种方法手术治疗增殖型糖尿病视网膜病变的疗效对比提供理论依据。方法选取2013年1月—2015年10月在郑州市第二人民医院接受治疗的172例增殖型糖尿病视网膜病变患者作为此次研究对象,随机平均分成观察组和对照组,各86例,对照组患者采用单纯25G玻璃体切割进行治疗,观察组患者采用玻璃体腔注射雷珠单抗后25G玻璃体切割联合内界膜剥除进行治疗,分析两组患者术后视力恢复情况,分析两组患者治疗前后最佳矫正视力变化情况,分析两组患者术后并发症情况。结果观察组总有效率为96.52%,对照组为74.42%,观察组明显要好,两组之间的数据资料存在较大差异,具有统计学意义(P<0.05);第1周和第14周观察组要明显好于对照组,两组存在差异,具有统计学意义(P<0.05);观察组总发生率为3.48%,对照组为11.63%,观察组明显要小,具有统计学意义(P<0.05)。结论增殖型糖尿病视网膜病变患者采用玻璃体腔注射雷珠单抗后25G玻璃体切割联合内界膜剥除进行治疗,疗效显著,患者视力恢复能力强,最佳矫正视力最好,术后并发症少,临床治疗中对此方法值得推广。

Objective To investigate the efficacy of surgical treatment of two methods proliferative diabetic retinopathy,provide a theoretical basis for comparison of the efficacy of treatment with proliferative diabetic retinopathy surgery for both methods.Methods In January 2013 to October 2015,the hospital treated 172 cases of patients with proliferative diabetic retinopathy as the object of study,were randomly divided into observation group and control group,86 cases in the control group were treated with pure 25G vitrectomy for treatment,after the observation group were treated with intravitreal ranibizumab injection 25G vitrectomy with internal limiting membrane peeling treatment,analysis of postoperative visual acuity,the two groups of patients before and after the change in BCVA,analyzed two groups of patients after surgery complications.Results The total effective rate was 96.52% in observation group,the control group was 74.42%,significantly better than that of the observation group,the difference was statistically significant（P 0.05）; the first one week and 14 week observation group was significantly better than the control group,the difference between two groups,with statistical significance（P 0.05）; In observation group,the total incidence of 3.48% in the control group was 11.63% in the observation group was significantly smaller,with statistical significance（P 0.05）.Conclusion Patients with proliferative diabetic retinopathy using intravitreal ranibizumab after 25G vitrectomy with internal limiting membrane peeling treatment,has a significant effect,strong visual acuity recovery capabilities,best visual acuity,fewer complications,clinical treatment should be promoted.