冠状动脉狭窄程度与左心形态及心脏收缩功能的关系

Relationship between left ventricular morphology, systolic function and severity of coronary artery lesions

目的 :探讨冠状动脉不同病变程度与左心形态及收缩功能的关系。 方法 :对 1997～ 2 0 0 1年间行选择性冠状动脉造影的 5 89例住院患者 ,剔除风湿性心脏病、高血压性心脏病后 ,进行冠状动脉病变程度与左心形态及收缩功能关系的分析。并使用 SPSS10 .0统计软件分析包进行数据的 R× C表χ2 检验、均值的 t检验、One- Way ANOVA方差分析和相关性分析。 结果 :冠状动脉病变积分、病变支数、病变分型与左室短轴缩短率 (FS)、左室射血分数 (EF)呈负相关 ,与左房收缩末期内径(L ADS)、左房舒张末期内径 (L ADD)、左室收缩末期内径 (L VDS)、左室舒张末期内径 (L VDD)呈正相关 (P<0 .0 1)。冠状动脉造影阳性组中 EF、FS均值较低 ,L ADS、L ADD、L VDS均值较高。而且冠状动脉病变支数越多及冠状动脉狭窄介入治疗的难度越高 ,EF、FS的均值降低及 L ADS、L ADD、L VDS、L VDD的均值升高越明显。结论 :冠状动脉狭窄可引起心肌收缩功能减弱及心脏扩大 ,并随着狭窄程度的增加而加重 ;

Objective:To investigate the relationship between the left ventricular morphology, systolic function and the severity of the coronary artery lesions. Methods:A total of 589 consecutively admitted patients were studied retrospectively. All patients suspected of coronary artery disease underwent a selective coronary angiography and a survey of left ventricular ejection fraction (EF) during the hospitalization. Results:A significant correlation between the severity of the coronary artery lesions and the EF, FS, LADD, LADS, LVDS and LVDD was found through the Bivariate Correlation analysis ( P <0.01). Conclusion:The severer the coronary artery lesions are, the lower EF and FS are and the higher LADD, LADS, LVDS and LVDD are.