中医辅助治疗对妊娠期糖尿病临床有效性指标的影响

effect of Traditional Chinese Medicine Adjuvant Therapy on Gestational diabetes Mellitus Clinical effectiveness Index

目的:观察在西医治疗(胰岛素治疗)的基础上给予中医治疗对妊娠期糖尿病患者的临床疗效评价,并评估其安全性及母婴结局。方法:选取符合标准的妊娠期糖尿病患者100例,随机分为观察组和对照组,每组各50例。.对照组给予生物合成人胰岛素+门冬胰岛素治疗,观察组在此基础上给予口服中药汤剂,比较2组患者治疗前与治疗过程中3餐后2h血糖变化,并比较2组患者治疗过程中的不良反应及其母婴结局。结果:餐后2h血糖比较显示2组患者均无统计学差异(P>0.05),2组患者的血糖达标时间、分娩孕周等指标均无统计学差异(P>0.05),观察组胰岛素用量与体重增加量均低于对照组(P<0.05),2组患者的满意度调查结果显示观察组优于对照组(P<0.05),2组患者治疗过程中发生餐前低血糖、皮疹等不良事件均无统计学差异(P>0.05),2组患者的母婴结局均无统计学差异(P>0.05)。结论:胰岛素治疗的基础上给予中药汤剂治疗能减少胰岛素用量,安全可靠,患者满意率高。

Objective： To observe, on the basis of Western medical treatment（insulin treatment）, the clinical efficacy of traditional Chinese medicine（TCM） for gestational diabetes mellitus and evaluated the safety and maternal and infant outcomes. Methods： 100 cases of gestational diabetes mellitus were selected and randomly divided into observation group and control group with 50 cases in each group. Methods： 100 cases of gestational diabetes mellitus were selected and randomly divided into observation group and control group with 50 cases in each group. The control group was given biosynthetic human insulin plus insulin aspart. On the basis of this, the observation group was given oral Chinese medicine decoction, and the changes of blood glucose 2 h after 3 meals were compared between the two groups before and after treatment. Adverse reactions and maternal-infant outcomes were compared between the two groups during treatment. Results： 2 h postprandial blood glucose showed no significant difference between the two groups（P0.05）.Two groups of patients with blood glucose compliance time, gestational birth gestational age and other indicators were not statistically different（P0.05）. Insulin dosage and weight gain in the observation group were lower than those in the control group（P0.05）. Two groups of patients satisfaction survey results showed that the observation group was better than the control group（P0.05）. There were no significant differences in the incidence of premenstrual hypoglycemia and rash between the two groups during treatment（P0.05）. There was no significant difference between the two groups in maternal and infant outcomes（P0.05）. Conclusion： The insulin treatment based on the Chinese medicine decoction can reduce the amount of insulin, safe and reliable, patients with high satisfaction.