pop—off现象对后尿道瓣膜症患儿肾功能预后的影响

Influence of pop-off mechanisms on renal functions in children with posterior urethral valves

后尿道瓣膜症是男童先天性下尿路梗阻中最常见的疾病，可导致肾发育不良及膀胱功能异常，是导致儿童终末期肾衰竭最常见的原因。尽管经尿道镜瓣膜切除术可有效解除尿路梗阻，但患儿术后常合并膀胱功能异常及肾功能不全，膀胱功能及远期。肾功能预后受诸多因素影响，难以预测。近年来，pop-off现象对PUV患儿预后的影响仍存在争议，本文对此做一综述。

As one of the most common causes of bladder outlet obstruction in infants, posterior urethral valve （PUV） impairs renal and bladder functions and leads to end-stage renal disease in children. After primary valve ablation, many PUV patients develop bladder dysfunction and renal impairment. It remains challenging to predict the long-term outcomes. In recent years, the effects of pop-off mechanisms on renal fuhction have been debated. The aim of this review is to offer a general overview.