摘要
儿童肺动脉高IN,(PAH)与多种诱因有关,发病率和病死率均较高,随着新型PAH药物的发现和循证依据充分指南的制定,成人PAH生存率得到明显改善。但儿童PAH在病理生理、潜在因素、临床表现及最终预后方面都有明显不同。为儿童PAH制定目标导向性治疗,对改变儿童PAH不良预后具有重要意义。本文就儿童肺高压目前的诊治进展进行综述。
Pulmonary arterial hypertension (PAH) in children is associated with various underlying diseases and unknown causes and leads to significant morbidity and mortality. With the discovery of novel drugs and the formulation of evidence-based guidelines, the survival of adult PAH has improved significantly. However, children and adults vary greatly in pathophysiological causes, precipitating factors, clinical manifestations and ultimate outcomes. For achieving a better prognosis in children, offering goal-oriented treatments are essential. This review provides an overview of recent advances of diagnosing and treating PAH in children.
出处
《中华小儿外科杂志》
CSCD
北大核心
2018年第2期155-159,共5页
Chinese Journal of Pediatric Surgery
关键词
肺动脉高压
先天性心脏病
儿童
Pulmonary hypertension
Heart disease, congenital
Child