期刊文献+

Graves′病患者血清Ⅰ型胶原相关肽水平研究及临床意义

下载PDF
导出
摘要 目的 :探讨 Graves′病毒患者血清中 型胶原蛋白相关肽的代谢规律及临床意义。方法 :采用放射免疫分析法 (RIA)检测 5 1例 Graves′病毒患者及 35例健康体检者血清 型胶原羧端肽 (ICTP)及 型原胶原羧端延长肽(PICP)水平 ,同时测定 Ca2 +、P3 +、AKP。结果 :Graves′病患者组 ICTP及 PICP均较健康组非常显著升高 (P<0 .0 1) ,ICTP及 PICP水平与 FT3水平均呈正相关 (r=0 .5 6 3和 0 .5 15 ) ,血清 Ca2 +、P3 +值两组间无明显差异 (P>0 .0 5 ) ,Graves′病组血清 AKP较对照组显著升高 (P<0 .0 5 )。结论 :Graves′病患者骨吸收及骨形成呈高度活跃状态 ,检测ICTP和
出处 《临床医药实践》 2002年第7期497-498,共2页 Proceeding of Clinical Medicine
  • 引文网络
  • 相关文献

参考文献4

  • 1李梅,孟迅吾,周学瀛.Ⅰ型胶原蛋白与骨质疏松症研究进展[J].国外医学(内分泌学分册),2000,20(1):14-17. 被引量:34
  • 2Allain TJ,Yen PM,Flanagan AM et al. The isofotmspecific expression of the tri-iodothyronine receptor in osetoblasts and osteoblasts[J]. Eur J Invest, 1996,26:418~425.
  • 3Celik I,Akalin S,Aizawa T. Serum levels of interleukin-6 and tumor-necrosis factor in hyperthyroid patients before and after prcpyhhiouracil treatment[J]. Eur J Endocrinol, 1995,12: 668~ 672.
  • 4Persani L,Preziati D,Matthews CH et al. Serum levels of carboxyterminal cross-linked telopeptide of type I collagen (ICTP) in the differential diagnosis of the syndromes of inappropriate secretion of TSH[J]. Clin Endocrinol, 1997,47: 207~ 214.

二级参考文献4

  • 1H. Hoshino,M. Takahashi,K. Kushida,T. Ohishi,T. Inoue. Urinary Excretion of Type I Collagen Degradation Products in Healthy Women and Osteoporotic Patients with Vertebral and Hip Fractures[J] 1998,Calcified Tissue International(1):36~39
  • 2F. Cosman,J. Nieves,C. Wilkinson,D. Schnering,V. Shen,R. Lindsay. Bone density change and biochemical indices of skeletal turnover[J] 1996,Calcified Tissue International(4):236~243
  • 3Lieve Nuytinck,Raymond Dalgleish,Loretta Spotila,Jean-Pierre Renard,Nicole Regemorter,Anne Paepe. Substitution of glycine-661 by serine in the α1(I) and α2(1) chains of type I collagen results in different clinical and biochemical phenotypes[J] 1996,Human Genetics(3):324~329
  • 4C. Fledelius,B. J. Riis,K. Overgaard,C. Christiansen. The diagnostic validity of urinary free pyridinolines to identify women at risk of osteoporosis[J] 1994,Calcified Tissue International(5):381~384

共引文献33

;
使用帮助 返回顶部