丙泊酚联合芬太尼在上消化道超声内镜检查中镇静效果观察

Sedative Effect of Propofol Combined with Fentanyl on Patients in Endoscopic Ultrasonography Examination of Upper Gastrointestinal Tract

目的研究消除患者焦虑心理的超声内镜检查麻醉过程中丙泊酚联合芬太尼合用麻醉效果及安全性。方法 60名接受超声内镜检查患者随机分为两组(丙泊酚+芬太尼组与丙泊酚单用组)。术前对焦虑、恐惧患者给予心理干预;术中麻醉开始后观察:总麻醉时间、麻醉深度、药物总剂量,患者缺氧及血压变化情况。麻醉结束后观察患者生命体征、心电图和消化道反应情况等。结果丙泊酚联合芬太尼与丙泊酚单独使用的麻醉效果和并发症发生率差异无统计学意义。结论与丙泊酚单独使用相比,联合应用芬太尼尽管可以减少丙泊酚的用量,但超声内镜麻醉期间丙泊酚与芬太尼合用未能产生更好的麻醉效果,同时也未能降低并发症的发生。

Objective To investigate the anesthetic effect and safety of propofol combined with fentanyl during the anesthesia in the endoscopic uhrasonography examination which may relieve patients from anxiety. Methods 60 patients undergoing endoscopic ul- trasound were randomly divided into two groups, propofol ＋ fentanyl group and propofol group. The patients with preoperative anxiety and fear were given psychological intervention before operation. When the anesthesia began, the total anesthesia time, anesthesia depth, total drug dose, hypoxia in patients, and change of blood pressure were observed. The vital signs, ECG and gastrointestinal reactions of patients were observed when the anesthesia ended. Results There was no statistically significant difference in the anes- thetic effect and the incidence of complications between the two group. Conclusions Compared with propofol alone, propofol com- bined with fentanyl can reduce the dosage of propofol, but cannot produce a better anesthetic effect during the examination of endoscop- ic uhrasonography, or reduce the incidence of complications.