探讨检测凝血和纤溶功能对慢性阻塞性肺疾病患者病情和并发症的临床价值研究

To Investigate the Clinical Value of Detecting Coagulation and Fibrinolytic Function in Patients with Chronic Obstructive Pulmonary Disease

目的探讨检测凝血和纤溶功能对慢性阻塞性肺疾病患者的病情和并发症的临床价值研究。方法选取2015年12月至2016年12月沈阳市第十人民医院就诊的慢性阻塞性肺疾病患者100例分为COPD稳定组50例和COPD合并肺栓塞组50例,另选取50例健康体检患者作为对照组,比较两组患者的测凝血和纤溶功能。结果两组患者观察指标比较,COPD稳定组和COPD合并肺栓塞组的PT、a PTT、Fbg、D-D值均高于对照组,差异有统计学意义(P<0.05)。COPD稳定组和COPD合并肺栓塞组比较,COPD合并肺栓塞组值高于COPD稳定组,差异有统计学意义(P<0.05)。结论 COPD患者凝血和纤功能异常,凝血和纤溶功能可以作为COPD的诊断和鉴别。

Objective To study the detection of blood coagulation and fibrinolytic function in patients with chronic obstructive pulmonary disease and complications of the clinical value of research. Methods Select in December 2015 to December 2016, the tenth people＇s hospital in shenyang, 100 cases of patients with chronic obstructive pulmonary disease in stable COPD groups 50 cases with COPD with pulmonary embolism group of 50 cases, the other selected 50 cases of healthy check-up patients as control group, compared two groups of patients of blood coagulation and fibrinolytic function. Results Two groups of patients to observe more, stable COPD and COPD with pulmonary embolism group of PT, a PTT and Fbg, D-D values are higher than the control group, the difference was statistically significant（P〈0.05）. Stable COPD and COPD with pulmonary embolism group comparison, COPD with pulmonary embolism group values higher than the stable COPD group, the difference was statistically significant（P〈0.05）. Conclusion Abnormal blood clotting and fiber function in patients with COPD, coagulation and fibrinolytic function can be used as COPD diagnosis and differential.