对接受腹腔镜胆囊切除术的患者施行全麻前为其应用戊乙奎醚对其心率的影响

The effects to the heart rate of applying penehyclidine before general anesthesia to the patients accepting laparoscopic cholecystectomy

目的:观察对接受腹腔镜胆囊切除术的患者施行全麻前为其应用戊乙奎醚对其心率的影响。方法 :将近年来在安徽省泗县人民医院进行全麻下腹腔镜胆囊切除术的60例慢性胆囊炎、胆石症患者随机分为A组与B组,每组各30例患者。在对A组患者进行全麻前为其应用戊乙奎醚,在对B组患者进行全麻前为其应用阿托品,然后对比观察为两组患者给药(戊乙奎醚或阿托品)前、给药5分钟时、对胆囊进行手术操作时及完成手术操作时其心率的变化情况。结果 :在给药前,两组患者的平均心率相比差异无统计学意义(P>0.05)。与A组患者相比,在给药5 min时、对胆囊进行手术操作时和完成手术操作时B组患者的平均心率均较快(P<0.05)。结论 :对接受腹腔镜胆囊切除术的患者施行全麻前为其应用戊乙奎醚不会明显加快其心率,用药的安全性较高。

Objective To study the effects the heart rate of applying penehyclidine before general anesthesia to the patients accepting laparoscopic cholecystectomy. Methods Divide 60 case of patients with chronic cholecystitis or cholelithiasis to 2 group A and group B,30 cases each group. Apply penehyclidine before general anesthesia to group A, apply atropine to group B, then observe and compare heart rate change at the time points of pre-dose,5 minutes after dosed, during operation and after operation. Results At the time point of pre-dose, there is no statistical significant of heart rate between 2 groups（P〉0.05）. Compare with group A, heart rate of group B are faster at the points of 5 minutes after dosed, during operation and after operation（P〈0.05）. Conclusion Apply penehyclidine before general anesthesia to the patients accepting laparoscopic cholecystectomy will not accelerate heart rate, it have a high safety.