生殖系统CT、UU、NG三种病原体感染现状分析

Analysis of the prevalence of CT, UU and NG in reproductive system

目的了解柳州地区沙眼衣原体(CT)、解脲脲原体(UU)和淋球菌(NG)3种主要生殖系统疾病病原体的感染现状,为临床防治提供依据。方法对2014年1月至2016年12月来我院就诊的47 618例患者样本,采用实时荧光定量PCR技术检测CT、UU及NG 3种病原体,并对检测结果进行统计分析。结果3种病原体中,UU的阳性率最高(61.50%),NG和CT的阳性率均较低(3.29%、10.90%)。在不同性别中,女性患者CT、UU和NG的阳性率均高于男性患者(P<0.05)。男性和女性患者均为15~20岁年龄组CT阳性率较高。男性患者各年龄组间UU阳性率差异无统计学意义,女性患者15~20岁年龄组UU阳性率较高。男性高NG阳性感染者主要集中于21~40岁年龄段,女性患者51岁以上年龄组NG阳性率较高。在女性患者中,诊断为生殖系统炎症或不孕症的患者CT、UU、NG的阳性检出率均高于整体的平均检出率,体检、婚检女性人群3种病原体阳性检出率均接近于平均检出率。此外,CT在夏季的阳性检出率最高,而UU和NG各季节间比较差异无统计学意义。结论 CT、UU、NG感染均与生殖系统疾病和不孕症密切相关,应注意个人防护及重视体检,积极防治。

Objective To learn about the infection status of 3 common sexually transmitted diseas- es （STD） pathogens of Neisseria gonococcus （NG）, Chlamydia trachomatis （CT） and Ureaplasma urealyticum （UU） in Liuzhou city and provide evidence for the prevention and treatment of these STDs. Methods CT, UU and NG samples were taken routinely from 47 168 patients admitted to our hospital from January 2014 to December 2016, and determined by quantitative real-time PCR （qPCR） as contrast. Results Among 47 618 patients, the detection rate of UU was the highest （61.50%）, the detection rates of NG and CT were lower （3.29%, 10.90% respectively）. The detection rates of CT, UU and NG were all lower in males than in females （P〈0.05）. The CT detection rate of patients aged 15 to 20 was the highest in both males and females. There were no significant differences among the results of the infection rate of UU in males, and in females, the high- est positive rate of UU was in the 15 to 20 age group. The highest positive infection rate of NG in males was predominantly in the 21 to 40 age group, while the detection rate of NG in t〉51 years old females was the highest. In female patients, the diagnosis of reproductive system inflammation and infertility accounted for a larger proportion, and the detection rates of CT, UU and NG were all higher than the overall detection rates, detection rates of the examination group are close to the total detection rates. The detection rate of CT was the highest in summer. There were no significant differences among the results of UU and NG in different seasons. Conclusion The infection of CT, UU and NG are closely related to the diagnosis of reproduc- tive system inflammation or infertile patients. We should pay attention to personal protection and physi- cal examination.