辛伐他汀治疗冠心病心绞痛急性发作的临床效果

Clinical effect of simvastatin in the treatment of acute attack of angina pectoris and coronary heart disease

目的探讨辛伐他汀治疗冠心病心绞痛急性发作的临床效果。方法选取2015年5月至2016年5月我院收治的72例冠心病心绞痛急性发作患者为研究对象,随机分为试验组与对照组,各36例。对照组患者实施常规治疗,试验组在对照组基础上加用辛伐他汀。比较两组患者的临床疗效。结果试验组的治疗总有效率为97.22%,显著高于对照组的72.22%(P<0.05);治疗后,两组患者的心绞痛发作持续时间、发作次数、TG及TC水平均明显优于治疗前,且试验组明显优于对照组(P<0.05)。结论对冠心病急性心绞痛发作患者实施辛伐他汀治疗,能够明显缓解患者的心绞痛发作症状,改善患者的TG、TC水平,值得在临床上推广应用。

Objective To investigate the clinical effect of simvastatin in the treatment of acute attack of angina pectoris and coronary heart disease. Methods Seventy-two cases of patients with acute attack of angina pectoris and coronary heart disease admitted in our hospital were selected and randomly divided into experimental group and control group, with 36 cases in each group. The control group was treated with routine treatment, and the experimental group was given simvastatin on the basis of the control group. The clinical effects of the two groups were compared. Results The total effective rate of the experimental group was 97.22%, which was higher than 72.22% of the control group（P 0.05）. After treatment, the duration and attack times of angina pectoris, levels of glycerin triacylglycerol（TG） and total cholesterol（TC） in the two groups were better than those before treatment, and those in the experimental group were better than the control group（P〈0.05）. Conclusion Using simvastatin in the treatment of acute attack of angina pectoris and coronary heart disease can obviously relieve the symptoms of angina pectoris, and improve the TG and TC levels, which is worth popularizing in clinic.