醒脑静注射液对脑梗塞患者神经功能及脑血流动力学的影响

Effect of Xingnaojing injection on nerve function and cerebral hemodynamics in patients with cerebral infarction

目的探讨醒脑静注射液对脑梗塞患者神经功能及脑血流动力学的影响。方法选取2016年1月至2017年3月于我院就诊的96例脑梗塞患者为研究对象,将患者随机分为试验组和对照组,各48例。对照组患者采用常规西药治疗,试验组患者在此基础上给予醒脑静注射液。比较两组患者治疗前、后的神经功能和脑血流动力学各指标水平。结果治疗后,两组患者的神经功能缺损评分均显著低于治疗前,且试验组明显低于对照组(P<0.05);治疗后,两组患者的最大峰值流速、舒张末流速、血管阻力指数和血管搏动指数均明显优于治疗前,且试验组明显优于对照组(P<0.05)。结论醒脑静注射液治疗脑梗塞疗效满意,能显著减少神经功能缺损,改善脑血流动力学,值得临床推广。

Objective To explore effect of Xingnaojing injection on nerve function and cerebral hemodynamics in patients with cerebral infarction. Methods Ninety-six cases of patients with cerebral infarction in our hospital from January2016 to March 2017 were selected and randomly divided into experimental group and control group, with 48 cases in each group. The control group was treated with routine western medicine, and the experimental group added Xingnaojing injection. The nerve function and cerebral hemodynamics of the two groups before and after treatment were compared.Results After treatment, the neurological impairment scores of the two groups were lower than those before treatment, and that of the experimental group was lower than the control group（P〈0.05）. After treatment, the maximum peak flow velocity,diastolic flow velocity, vascular resistance index and vascular pulsation index of the two groups were better than those before treatment, and those of the experimental group were better than the control group（P〈0.05）. Conclusion The clinical effect of Xingnaojing injection in patients with cerebral infarction is satisfactory, it can reduce neurological impairment and improve cerebral hemodynamics, which is worthy of clinical popularization.