阿托伐他汀与氯吡格雷联合应用于脑梗塞治疗中的效果分析

Effect analysis of atorvastatin combined with clopidogrel in the treatment of cerebral infarction

目的分析阿托伐他汀与氯吡格雷联合应用于脑梗塞治疗中的效果。方法选取我院2016年3月至2017年3月收治的72例脑梗塞患者作为研究对象,按照治疗方式的不同将其分为研究组与对照组,各36例。对照组行常规治疗,研究组基于常规治疗行阿托伐他汀与氯吡格雷联合治疗。比较两组治疗总有效率与治疗前、后神经功能缺损评分、日常生活能力评分。结果研究组患者治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者的神经功能缺损评分均降低,且研究组低于对照组(P<0.05)。治疗后,两组患者的日常生活能力评分均升高,且研究组高于对照组(P<0.05)。结论阿托伐他汀与氯吡格雷联合应用于脑梗塞治疗中的效果显著,可有效改善患者的神经功能缺损情况与日常生活能力,提升患者的临床治疗效果,值得在临床治疗工作中推广运用。

Objective To analyze the effect of atorvastatin combined with clopidogrel in the treatment of cerebral infarction. Methods A total of 72 patients with cerebral infarction treated in our hospital from March 2016 to March 2017 were selected as the research objects, and all the patients were divided into study group and control group according to the different treatment methods, with 36 cases in each group. Patients in the control group received routine treatment, while patients in the study group were treated with atorvastatin combined with clopidogrel on the basis of routine treatment. The total effective rates, neurological deficit scores and daily life ability scores before and after treatment were compared in the two groups. Results The total effective rate of treatment in the study group was higher than that in the control group, the difference was statistically significant（P〈0.05）. After treatment, the scores of neurological deficit in both groups decreased, and that of the study group was lower than the control group（P〈0.05）. After treatment, the daily life ability scores of both groups increased, and that of the study group was higher than the control group（P〈0.05）. Conclusion Atorvastatin combined with clopidogrel in the treatment of cerebral infarction has significant effect, which can not only be effective to improve the neural function defect and daily life ability of patients, but also further enhance patients＇ clinical effect of treatment. It is worthy of clinical application.