利多卡因联合丙泊酚在喉镜手术麻醉中的效果分析

Effect of lidocaine combined with propofol in the anesthesia of laryngoscope surgery

目的探讨利多卡因联合丙泊酚在喉镜手术麻醉中的效果。方法收集我院2015年1月至2016年6月收治的80例需行支撑喉镜手术患者,随机分为观察组与对照组,各40例。麻醉诱导维持时,观察组患者采用丙泊酚(内含2 mg/m L利多卡因),对照组组单用丙泊酚,心电监护观察两组围麻醉期的血流动力学变化情况。结果 T_2,T_3,T_4,T_5时,观察组患者的MAP低于对照组,HR低于对照组(P<0.05);与T0时比较,T_1时两组患者的MAP与HR均降低(P<0.05);观察组T_2,T_3,T_4,T5_时的MAP与HR与T0时比较,无明显变化(P>0.05);对照组T_2,T_3,T_4,T_5时的MAP与HR均高于T0时(P<0.05)。结论在喉镜手术中采用利多卡因联合丙泊酚维持麻醉,有利于保持患者血流动力学平稳。

Objective To explore the effect of lidocaine combined with propofol in the anesthesia of laryngoscope surgery. Methods From January 2015 to June 2016, 80 patients undergoing laryngoscope surgery in our hospital were selected and randomly divided into observation group and control group, with 40 cases in each group. When induction of anesthesia was maintained, patients in the observation group received propofol（containing 2 mg/m L lidocaine）, and the control group received propofol alone. The hemodynamic changes during the perioperative anesthesia with ECG were observed. Results At T_2, T_3, T_4 and T_5, the MAP in the observation group were lower than those in the control group, HR were lower than those in the control group（P〈0.05）; compared with T_0, the MAP and HR in T_1 in both groups decreased（P〈0.05）; compared with T0, the MAP and HR at T_2, T_3, T_4 and T_5 in the observation group had no significant change（P〈0.05）;the MAP and HR at T_2, T_3, T_4 and T5_ in the control group were higher than those at T_0（P〈0.05）. Conclusion The application of lidocaine combined with propofol to maintain anesthesia in laryngoscopic surgery is conducive to maintain the patients＇ hemodynamic stability.