摘要
目的观察平肝化浊浴足方治疗高血压病的疗效及对血脂的影响。方法选取上海市第六人民医院金山分院中医内科门诊高血压病证(肝火亢盛夹痰浊型)病人60例,随机分为治疗组和对照组,对照组口服左旋氨氯地平片和辛伐他汀片,治疗组在对照组的基础上加用平肝化浊浴足方浴足,每晚1次,共治疗6个月。观察两组治疗前后血脂变化,比较两组降压疗效。结果两组治疗后总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)较治疗前明显降低,高密度脂蛋白胆固醇(HDL-C)较治疗前明显升高,差异有统计学意义(P<0.05);与对照组治疗后比较,治疗组TC、TG、LDL-C明显降低(P<0.05),HDL-C差异无统计学意义(P>0.05)。治疗组总有效率为76.67%,高于对照组的66.67%,差异有统计学意义(P<0.05)。结论平肝化浊浴足方降低高血压病人血压的同时,能更好地调节血脂。
Objective To observe the effect of Pinggan Huazhuo Yuzu decoction(PHYD)on blood lipid in patients with essential hypertension(EH).Methods Sixty patients with EH and syndrome of hyperactivity of liver-fire and phlegm-turbid from Jinshan Branch of Shanghai Sixth People’s Hospital were randomly divided into two groups:control group treated with levamlodipine besylate and simvastatin,and treatment group treated with levamlodipine besylate,simvastatin and PHYD for 6 months.Blood pressure and blood lipid were observed before and after treatment.Results The levels of total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C)were decreased in two groups after treatment while high-density lipoprotein cholesterol(HDL-C)levels were increased(P 〈0.05).The levels of TC,TG,LDL-C were lower in treatment group than that in control group(P 〈0.05).The total clinical effective rate was higher in treatment group than that in control group(76.67% vs 66.67%,P 〈0.05).Conclusion PHYD can reduce blood pressure and regulate blood lipid in patients with EH.
出处
《中西医结合心脑血管病杂志》
2018年第4期436-438,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
基金
上海市卫生和计划生育委员会中医药科研基金(No.2014LP028A)
关键词
高血压病
肝火亢盛夹痰浊型
平肝化浊浴足方
血脂
眩晕
essential hypertension
syndrome of hyperactivity of liver-fire and phlegm-turbid
Pinggan Huazhuo Yuzu decoction
blood lipid
dizziness