应用ET技术评价高血压病患者早期颈动脉弹性功能的意义

Evaluation of Early Carotid Elastic Function in Patients with Hypertension by ET Technique

目的:探讨血管跟踪技术(Echo-tracking,ET)评价高血压病患者早期颈动脉血管弹性的应用价值。方法:高血压患者78例,根据颈动脉内-中膜厚度(IMT)分为两组,A组(n=36):IMT≤1.0mm,B组(n=42):IMT>1.0mm,正常对照组75例健康人。应用ET检测三组人群的颈动脉硬化参数,包括弹性系数(Ep)、僵硬度(β)、顺应性(AC),通过观察这些参数的变化,评估高血压患者颈动脉弹性功能。结果:A组和B组的Ep、β值均高于对照组,有显著性差异;A组和B组的AC值低于对照组,亦有显著性差异。B组的Ep、β值高于A组,两组比较有显著性差异,而AC值低于A组,并有显著性差异。结论:高血压病患者的颈动脉弹性功能采用ET技术进行检测,可以准确的定量评价颈总动脉弹性,反应高血压病患者血管内皮功能受损情况,对临床及早采取相应干预措施,为高血压患者血管并发症的早期预测提供了实用、简便而客观的方法。

Objective： To explore value of E-tracking（ET） technology in evaluating the carotid elasticity in hypertensive patients. Methods： Seventy-eight hypertensive patients were divided into two groups according to the intima-media thickness（IMT） of carotid artery,group A（36 cases） ： IMT≤1.0 mm,group B（42 cases） ： IMT〉1.0 mm,and normal control group（75 cases）. Using ET technology to track the movement of common carotid arterial wall and measure the parameters： stiffness parameters（β）,elastic coefficient（Ep）,and arterial compliance（AC）. Results： The values of Ep and β in group A and group B were significantly higher than those in control group. The AC values in group A and group B were lower than those in control group,and there were also significant differences. The values of Ep and β in group B were higher than those in group A,there was a significant difference between the two groups,while the AC value was lower than that in group A,with significant difference. Conclusions： ET technology can reflect the vascular endothelial function earlier. It is a simple and useful method in evaluating the vascular changes of hypertensive patients.