广州市6～9岁儿童骨骼肌含量指标正常参考值研究

Reference values of skeletal muscle mass indices in Chinese children aged 6-9 years in Guangzhou

目的建立广州市6~9岁儿童肌肉含量的参考值,为评价儿童肌肉发育情况提供依据。方法在广州市小学及幼儿园招募456名6~9岁儿童,采用双能X线吸收法(DXA)测量儿童全身及四肢肌肉含量(ASM),并测量身高、体重,计算体质量指数(body mass index,BMI)及四肢肌肉含量指数(如ASM体重,ASM/身高2及ASM/BMI)。应用LMS曲线法建立男女童各部位肌肉含量及四肢肌肉含量指数的百分位曲线。结果随着年龄增加,不论男生还是女生各肌肉含量指标均增大;除6岁年龄段上下肢及四肢肌肉含量、ASM/体重、ASM/BMI,以及9岁年龄段的ASM/体重和ASM/BMI外,其余各年龄段指标男生均大于女生(P值均<0.05)。结论初步建立了6~9岁学龄儿童肌肉含量及肌肉指数的参考值,且随着年龄的增大,相应参考值也逐渐增大。可为评估儿童肌肉发育提供较为准确的参考。

Objective To establish the reference values of skeletal muscle indices of children aged 6-9 in Guangzhou,China,and to provide reference for their muscule development. Methods A total of 456 children aged 6-9 years old were enrolled in urban area of Guangzhou. Dual-energy X-ray absorptiometry（ DXA） was applied to determine whole body muscle mass（ WBM）,arms muscle mass,legs muscle mass,appendicular skeletal muscle mass（ ASM）. Weight and height were measured. BMI and skeletal muscle mass indices including ASM/height,ASM/weight,and ASM/BMI were calculated. LMS regression analysis was used to construct age-and gender-specific smooth percentile curve of the above-mentioned indices. Results All of the skeletal muscle mass measurements increased significantly with age in both genders. Apart from the indexes of ASM,ASM/weight,ASM/BMI in the group of 6 years old and ASM/weight,ASM/BMI in the group of 9 years old,the measures of boys were generally significantly higher than those of girls（ P〈0. 05）. Conclusion The reference values for skeletal muscle mass in children aged 6-9 years in Guangzhou can provide a correct reference for evaluating children＇s muscle development.