结核感染T细胞斑点试验在结核病诊断中的应用价值

The Application Value of T Cell Spot Test for Tuberculosis Infection in the Diagnosis of Tuberculosis

目的探讨结核感染T细胞斑点试验(T-SPOT试验)在结核病诊断中的应用价值。方法选取2016年11月—2017年11月来我院就诊的疑似结合病患者327例,全部患者均行结合菌素试验(TST)和T-SPOT试验检测,A组为TST检测结果,B组为T-SPOT检测结果,比较两组诊断结果的准确性。结果 B组检测方法的敏感性、特异性和准确性(85.22%,88.68%,87.46%)均明显高于A组(71.30%,72.17%,71.87%)(P<0.05)。结论 T-SPOT试验检测结核病具有积极的临床应用价值。

Objective To explore the value of T cell spot test （T-SPOT test） for tuberculosis infection in the diagnosis of tuberculosis. Methods From November 2016 to November 2017, 327 cases of patients with suspected disease in our hospital, all patients were treated with streptozotocin （TST） test and T-SPOT test. Group A was the result of TST detection, and group B was the result of T-SPOT detection, and the accuracy of the two groups was compared. Results The sensitivity, specificity and accuracy of the group B （85.22%, 88.68%, 87.46%） were significantly higher than those in the group A （71.30%, 72.17%, 71.87%） （P 〈 0.05）. Conclusion T-SPOT test has a positive clinical value for detection of tuberculosis.