维生素D与多囊卵巢综合征

Vitamin D and polycystic ovary syndrome

多囊卵巢综合征(polycystic ovary syndrome,PCOS)是妇科及生殖医学科常见的一种内分泌疾病,生殖功能障碍与糖脂代谢紊乱常同时存在,具有多起因、异质性。研究表明维生素D水平在PCOS患者中普遍低于正常值,且与PCOS人群的胰岛素抵抗(insulin resistance,IR)、肥胖、高雄激素血症、生殖力下降、远期并发症、卵巢功能及抑郁症发生等相关,通过维生素D补充治疗及生活方式改变或许可以改善上述情况,进而提高PCOS患者的生殖力及生活质量。

Polycystic ovary syndrome（PCOS） is a kind of reproductive dysfunction and glucose and lipid metabolism disorder of endocrine disease, which has the characteristic of multiple causes and heterogeneity. Vitamin D deficiency is common in women with PCOS, which may be associated with insulin resistance, obesity, hyperandrogenism, reproductive dysfunction, the long-term complications, ovarian function and depressive disorder and so on. There may be a place for vitamin D supplementation to alleviate the above and improve wellbeing in women with PCOS.