延时摄像技术的研究现状

Reseach progress of time-lapse monitoring system

延时摄像(time-lapse)技术被越来越多的胚胎学家运用于人类辅助生殖领域,可通过该技术动态观察胚胎发育的全过程,获取有效信息,进行胚胎形态学评估及动力学参数的研究。一些实验表明胚胎动力学参数与胚胎发育潜能密切相关,这能够指导优质胚胎的选择,提高妊娠结局。已有国内外生殖中心根据动力学参数建立各自妊娠结局预测模型,但未有统一有效的标准。此外,该技术的有效性及安全性仍缺乏有力证据的支持。

Time-lapse monitoring technology has been widely used in human assisted reproductive technology（ART）, which allows for dynamic observation of embryo development, acquisition of useful information and assists research on morphology evaluation and morphological parameters. Some experiments indicated that morphokinetic parameters can help to select high-quality embryos and improve pregnant outcomes for the reason that they were closely related with development potential. A number of clinics have reported validated implantation prediction algorithms according to dynamic parameters while without a unified and valid standard. Moreover, the effectiveness and security of time-lapse system requires definitive evidence to support. The research progress of time-lapse system was summarized in this review.