人体脂肪组织对骨密度的影响

The influence of fat mass on bone mineral density

目的探讨人体脂肪对骨密度的影响。方法将160例采用双能X线骨密度吸收仪(dual-energy X-ray absorptiometry,DXA)进行骨密度和身体成分分析的患者作为研究对象,根据脂肪指数将女性和男性患者平分为高脂肪指数组和低脂肪指数组,比较两组的股骨颈、全髋和腰椎骨密度。结果 54例高脂肪指数组女性的脂肪指数为(10.0198±1.6811)kg/m^2,身体脂肪百分比为(36.71±3.06)%;54例低脂肪指数组女性的脂肪指数为(6.7167±1.0130)kg/m^2,身体脂肪百分比为(30.05±3.76)%。26例高脂肪指数组男性的脂肪指数为(6.9240±0.9090)kg/m^2,身体脂肪百分比为(25.72±3.17)%;26例低脂肪指数组男性的脂肪指数为(4.8085±0.7368)kg/m^2;身体脂肪百分比为(21.55±2.39)%。女性高脂肪指数组的股骨颈、全髋和腰椎骨密度均显著高于低脂肪指数组(P<0.05);男性高脂肪指数组与低脂肪指数组的各部位骨密度差异无统计学意义(P>0.05)。结论女性脂肪量对股骨颈、全髋和腰椎骨密度有正面影响。

Objective To study the influence of fat mass on bone mineral density in patients aged ≥50-year-old. Methods 160 patients who had bone mineral density（ BMD） and body composition assessments were included in our study. Female and male participants were divided into the group with higher fat mass index（ FMI） and the group with lower FMIaccording to the fat mass/. BMD of femoral neck,total hip and lumbar spine was compared between the higher FMI group and lower FMIgroup in females and males. Results Fat mass/H^2 was（ 10. 0198 ± 1. 6811） kg/m^2 and fat mass % was（ 36. 71 ± 3. 06） % in the 54 female patients with higher FMI,and the fat mass/H^2 was（ 6. 7167 ± 1. 0130） kg/m^2 and fat mass % was（ 30. 05 ± 3. 76） % in the 54 female patients with lower FMI. The fat mass/H^2 was（ 6. 9240 ± 0. 9090） kg/m^2 and fat mass % was（ 25. 72 ± 3. 17） % in the 26 male patients with higher FMI and the fat mass/H^2 was（ 4. 8085 ± 0. 7368） kg/m^2 and fat mass % was（ 21. 55 ± 2. 39） % in the 26 male patients with lower FMI. Females with higher FMI had higher BMD at femoral neck,total hip and lumbar spine than females with lower FMI. There were no statistical differences between two male groups. Conclusion Fat mass had positive effect on BMD at femoral neck,total hip and lumbar spine in females.