摘要
埃洛石纳米管(Halloysite Nanotubes,HNTs)是一种天然的纳米管状材料,具有对环境友好、生物相容性好、细胞毒性小等特点,近年来该材料得到了广泛的应用。HNTs是生物相容性较好的"绿色"材料,成本低、来源广等优点使其成为制备生物复合材料中的添加剂,而且HNTs具有的空腔结构、表面电荷性质及表面吸附性为重金属离子、染料分子、有机分子等的分离富集提供有利条件。另外,HNTs及其衍生的生物复合材料在循环肿瘤细胞的富集上得到应用。为了更好地了解和利用埃洛石纳米管,本文介绍了埃洛石纳米管的物理化学性能,以及HNTs在分离富集、活性分子的载运与控制释放等方面的应用进展,并对埃洛石纳米管的发展及应用前景进行展望。
Halloysite nanotubes( HNTs),as a natural nano-tubular material,w ith a variety of advantages,such as environmental friendliness,biocompatibility,low cytotoxicity and so on,have been w idely used in recent years. As a kind of biocompatible "green"material,because of their low cost and abundant natural resources,HNTs can be used as excellent additives for biomaterials. Besides,nano-tubular structure,surface charge and adsorption properties provide favorable conditions for separation and enrichment of metal ions,dyes,organic compounds and so on. Even better,HNTs and HNTs-derived biomaterials have been used as absorbents to capture circulating tumor cells in recent studies. For better understanding and utilize the nanotube,w e introduce the structure and properties of HNTs in detail,and review their application in separation,loading and controlled release of active molecules,etc. in this paper. Finally,w e give a conclusion that HNTs ow n a splendid perspectives on future opportunities and promising applications.
出处
《化学进展》
SCIE
CAS
CSCD
北大核心
2018年第2期198-205,共8页
Progress in Chemistry
基金
国家自然科学基金项目(No.21675178
21475153
21575167)
广东省自然科学重点基金项目(No.2015A030311020)
广东省自然科学基金自由申请项目(No.2016A030313358)
广东省公益研究与能力建设专项基金项目(No.2015A030401036)
广州市民生科技重大专项资助项目(201604020165)资助~~
关键词
埃洛石纳米管
分离
富集
药物分子
肿瘤细胞
halloysite nanotubes
separation
enrichment
drug molecule
tumor cell