DWI-IVIM在局部进展期直肠癌新辅助放化疗疗效评估中的研究现状

Research status of DWI-IVIM for the curative effect evaluation of locally advanced rectal cancer to neoadjuvant chemoradiotherapy

新辅助放化疗后全直肠系膜切除术已经成为局部进展期直肠癌的标准治疗方式。不同患者对放化疗的敏感性存在差异。术前新辅助放化疗疗效的准确评估对制定后续个体化治疗方案具有重要意义。弥散加权成像-体素内不相干运动(DWI-IVIM)已应用于评估直肠癌新辅助放化疗效果、预测病理完全缓解等方面。本文就DWI-IVIM在局部进展期直肠癌新辅助放化疗疗效评估中的研究现状进行综述。

Preoperative neoadjuvant chemoradiotherapy（ NCRT） followed by total mesorectal excision is becoming the standard treatment for patients with locally advanced rectal cancer（ LARC）. The sensitivity of different patients to chemoradiotherapy（CRT） is different. The accurate evaluation of curative effect of preoperative NCRT is of great significance to the formulation of subsequently individualized treatment schemes. Diffusion weighted imaging-intravoxel incoherent motion（ DWI-IVIM） had been used for evaluating the effects of NCRT and predicting the pathological complete response and so on. The research status of DWI-IVIM for the curative effect evaluation of LARC to NCRT was reviewed in this article.