摘要
目的探讨显微镜辅助经外环口下精索静脉结扎术和口服迈之灵治疗精索静脉曲张Ⅰ、Ⅱ度伴不育患者的疗效。方法男性不育伴精索静脉曲张Ⅰ、Ⅱ度患者85例随机分成2组,A组:行显微镜辅助经外环口下精索静脉结扎术64例;B组:口服迈之灵片21例,每天2次,每次0.3 g,共6个月,对比分析两组疗效。结果A组术后5~30 d,疼痛不适等症状消失42例(77.8%),术后6个月曲张的精索静脉内径小于1.8 mm 58例(90.6%),精索静脉内径大于1.8 mm 6例(9.4%);术后6个月精子密度,a+b级精子和精子活率改善率分别为46.88%、40.63%和43.75%。B组口服迈之灵6个月后疼痛不适等症状消失5例(23.9%),曲张的静脉内径无变化,精子密度、a+b级精子和精子活率分别为14.29%、19.05%和14.29%。结论精索静脉曲张Ⅰ、Ⅱ度患者行显微镜辅助经外环口下精索静脉结扎术疗效明显优于口服迈之灵。
Objective To study the efficacy between microsurgical subinguinal varicocelectomy and Mai-Zhi-Ling capsule for infertility patients with varicocele. Methods The male infertile patients with varicocele gradeⅠ°-Ⅱ° were randomly divided into two groups. Group A included 64 paitents, and these patients underwent microsurgical subinguinal varicocelectomy. The 21 patients were included in group B who were given two pieces ofMai-Zhi-Ling capsule twice a day and last for 6 months. Comparison and analysis were made. Results Symptoms such as pain disappeared in 52 cases accounted for 81.2% in group A in 5~30 days after operation. The interior diameter of spermatic vein became less than 1.8 mm in 58 patients accounted for 90.6%, and interior diameter of spermatic vein were more than 1.8 mm in 6 patients, accounting for 9.4% in group A in 6 months after operation. The improvement rate on sperm density,average percentage of a＋b level sperm activity, and sperm activity in group A in 6 months after operation were 46.88%, 40.63% and43.75%, respectively. Symptoms such as pain in group B disappeared in 5 cases（23.9%） after 6 months. Diameter of spermatic vein didn＇t change. The improvement rate on sperm density, average percentage of a＋b level sperm activity, and sperm activity in group B were14.29%, 19.05% and 14.29%, respectively. Conclusion Microsurgical subinguinal varicocelectomy is significantly better than Mai-Zhi-Ling capsule on efficacy for patients with varicocele gradeⅠ°-Ⅱ°.
出处
《新疆医学》
2018年第1期62-64,共3页
Xinjiang Medical Journal
