代谢组学技术及其在重要寄生原虫研究中的应用

Metabolomics techniques and its application in research of important protozoan parasites

代谢组学是继后基因组学、转录组学和蛋白质组学之后迅速发展起来的一门新兴学科,由于其独特的优点,现已成为一种重要的研究手段,目前主要应用于药物研发、疾病监测与诊断等领域。随着代谢组学技术的逐渐成熟以及新的分析方法的逐步建立,代谢组学的应用越来越广,也逐渐应用到寄生虫学研究领域,尤其是与公共卫生学息息相关的寄生原虫。本文通过对代谢组学、代谢组学研究方法以及代谢组学在重要寄生原虫研究中的应用展开综述,旨在为进一步深入了解代谢组学这门技术,并为我们能够应用该技术解决寄生原虫领域的难题提供参考。

Metabolomics is a new discipline which has developed rapidly following post-genomic,transcriptomics and proteomics.It has become an important research method because of its unique advantages.It is mainly used in drug research and development,disease surveillance and other fields.In addition,with the gradual maturation of metabolomics technology and the gradual development of new analytical methods,the application of metabolomics has been more and more widely,and metabolomics technology has been gradually applied to the field of parasite research,especially for protozoan parasites.This paper summarizes metabolomics,metabolomics research methods,and the application of metabolomics in research of protozoan parasites,with the aims of further understanding of metabolomics technology,and providing reference basis for solving problems of protozoan parasites.