“医学微生物学”本科实验教学中生物安全的落实与实践

The implementation and practice of biological safety in the experimental curriculum of Medical Microbiology for undergraduate students

"医学微生物学"实验课的主要实验材料是病原微生物,因此实验室生物安全是本课程区别于其它实验课程的重要特征之一。因条件限制,我校以前的"医学微生物学"实验课只能安排在不具备生物安全防护等级的普通实验室中进行,不仅存在安全隐患,也使一部分内容不能正常进行,使医学微生物实验教学的发展遇到了瓶颈。为解决这一矛盾,本研究通过医学微生物学教学师资队伍的培训、实验室硬件条件升级改造以及对课程内容涉及的菌(毒)种及其配套软件建设等一系列措施,建立了具有北京大学医学特色的"医学微生物学"实验教学新体系,保证了微生物实验室生物安全相关法规条例的落实及实验教学的正常进行。

Pathogenic microorganisms are the main material of laboratory exercises in Medical Microbiology, which means that the biological safety in the laboratory is the key character differing from that in other laboratory. Since the laboratory condition limited, previous laboratory exercises of Medical Microbiology used to be conducted in the ordinary laboratories which were not fully consistent with the Biological Safety Regulations, indicating in potential biosafety hazard for partial contents of laboratory exercises in Medical Microbiology, as well as being a bottleneck for development of medical microbiology experiment curriculum. In order to solve this problem, we have established the new experimental curriculum system of Medical Microbiology in Peking University through the training staffs, upgrading laboratory hardwares, evaluating the application of bacterial（viral） strains and constructing the software related to the content of the experiment, guaranteeing the regulations related to biological safety for experimental practices in microbiology laboratory.