青霉素利多卡因溶媒稳定性研究

Study on the Stability of Penicillin G potassium Injetion in tidocaine solution

对盐酸利多卡因作为青霉素G钾肌肉注射的溶媒,用经典恒温法做加速试验。所得数据以统计学方法进行一元线性直线回归,求出青霉素在其中的反应速度常数K和降解10%的时间t_(0.9),结果为:K25℃=1.3829×10^(-4),t_(0.9)=12.70h。

0.2% lidocaine hydrochloride solution was used as the solvent of penicillin Gpotassium.The stability of the injection was studied with classical constant tem-perature accelerated test.The data obtained were treated statistically, K_(25)℃=1.38×10^(-4) t_(0.9)=12.7h.