感染乙型肝炎病毒的育龄女性临床管理共识

Consensus on clinical management of hepatitis B virus- infected women of childbearing age

乙型肝炎病毒（HBV）母婴传播是导致慢性HBV感染的主要原因，对感染HBV的育龄女性妊娠前、妊娠期及产后进行规范管理，以实现HBV母婴“零”传播的目标。本共识内容包括：育龄女性和孕妇HBV筛查及治疗；妊娠期乙型肝炎活动的治疗；新生儿乙型肝炎免疫球蛋白和乙型肝炎疫苗联合免疫预防措施及评价；HBV携带且高病毒载量孕妇妊娠期抗病毒治疗及产后相关管理，并形成推荐意见，使临床医生对感染HBV育龄女性的临床管理标准化。

The mother-to-child transmission（MTCT） of hepatitis B virus （HBV） is the dominant cause of chronic HBV infection. In order to achieve the goal of ＂zero＂ MTCT before pregnancy, during pregnancy, and after pregnancy; standardized management for hepatitis HBV infection in women of childbearing age should be regulated. The content of this consensus includes： screening and treatment of HBV in pregnant women and women of childbearing age, treatment of hepatitis B during pregnancy, preventive measures and evaluation of combined immunization of hepatitis B immunoglobulin and hepatitis B vaccine in newborns, anti-viral therapy for all pregnant women with a high HBV DNA level and post-parttun period related management. In addition, 16 recommendations were formed for clinicians to standardize the clinical management of HBV infection in women of child-bearing age.