中药治疗视网膜静脉阻塞用药规律的探讨

Discussion on the Regularity of Chinese Herbal medicine in the Treatment of Retinal Vein Occlusion

目的总结和分析近10年内中国知识基础设施工程(CNKI)收录的中药治疗视网膜静脉阻塞的内服方剂中药物的用药规律及效果,指导临床遣方用药。方法收集相关文献,筛选并整理经临床验证有良好疗效的中药,建立治疗视网膜静脉阻塞的中药数据库,运用统计学方法分析其用药规律。结果高频药物主要有赤芍、当归、川芎、生地黄、三七、桃仁等;按功效分类,居于前列的为活血化瘀药、清热药、止血药、理气药、补血药、利水渗湿药;从药物性味归经来看,以苦寒、甘寒之品,归肝、心、肾经为多。结论经过初步探索和挖掘得出中医药治疗视网膜静脉阻塞的基本规律,治疗以活血化瘀、凉血止血及疏肝理气、利水消肿为法,气滞血瘀在视网膜静脉阻塞的病机中占有重要的地位。

Objective To summarize and analyze the laws and effects of traditional Chinese medicine in treating retinal vein occlusion（RVO） according to China national knowledge infrastructure（CNKI） published in the past 10 years for guiding the clinical medicine.Methods Collecting the relevant literature,screening and finishing clinical and effective Chinese medicine,setting up the TCM database and using statistical method to explore the regularity.Results The high frequently-used drugs for RVO including radix paeoniae rubra,angelica,ligusticum wallichii,radix rehmanniae,notoginseng,Peach Seed; Blood-activating,heat-clearing,hemostatic,qi-regulating,hematinic,water-expelling and dampness-draining were widely used.From the perspective of the tropism of taste,drugs are mostly cold,bitter and sweet tastes,drugs for liver,heart,kidney channels were prevailing.Conclusion The basic rules of TCM in the treatment of RVO had been obtained through the preliminary exploration and excavation.Promoting blood circulation to disperse blood stasis,cooling blood,stopping bleeding,dispersing the liver,rectifying qi and draining water were the principle of treatment,qi stagnation and blood stasis play important role in the pathogenesis of RVO.