儿童自闭症的生物学机制研究综述

Research for Children Autism Spectrum Diagnose

自闭症又称孤独症。自闭症是一种儿童早期广泛性脑功能发育障碍性疾病,具有种族、地域和个体差异性特点,未经干预治疗的自闭症患儿的终身残疾率很高。近年,儿童自闭症患病率的报道呈逐年上升趋势。但目前关于儿童自闭症的病因形成的机制尚不清楚。一般认为是多种非生物因素和生物因素共同影响作用的结果。其中以脑发展、神经化学和遗传等的生物因素占多数。本文仅就目前国内外对于自闭症和自闭症谱系障碍的定义和病因形成的非生物学因素及生物学因素研究做简要概述,希望为相关研究提供有价值的参考。

Autism Spectrum Diagnose, is also called aloneness disease, which belong to one disease of childhood extensive brain function disorders in early development. Autism possesses the characteristics of racially, geographic and individual differences, and the autism children who did not receive intervention treatment will cause the high rate of permanent disability. In recent years the reports about autism children prevalence rate have been increased. But the formation mechanism of autism children is still unclear. Generally considered it＇s the results of kinds of biological factors and non-biological factors influenced.,which the biological factors contain the brain development, neurochemistry and genetic factors are in the majority. This paper will discuss the current domestic and international non-biological factors and biological factors for the autism, the definition of autism lineage disorders and the cause of formation as a brief overview., so as to provide some valuable reference for correlative researches.