超声引导下注射富血小板血浆治疗顽固性肱骨外上髁炎的临床研究

Clinical study of ultrasound-guided injection of platelet-rich plasma for the treatment of recalcitrant lateral epicondylitis

目的探讨超声引导下富血小板血浆(PRP)对顽固性肱骨外上髁炎的临床疗效。方法 2014年9月至2016年6月,采用超声引导下注射患者自身PRP治疗顽固性肱骨外上髁炎患者15例,左臂2例,右臂13例,利用二次离心法离心患者自身静脉全血得到PRP,所有患者每周行1次PRP注射治疗,共计3次。结果患者在首次治疗后开始随访,治疗后1个月患者疼痛(VAS评分)显著改善,治疗后3个月患者疼痛改善最佳,并可持续至12个月,肘关节功能(改良MAYO肘关节功能评分)在治疗后1个月也得到显著改善,并且疗效持续至12个月。结论在超声引导下精确注射PRP可有效改善顽固性肱骨外上髁炎的疼痛和肘关节功能障碍。

Objective To explore the clinical efficacy of ultrasound-guided injection of platelet-rich plasma（PRP） for the treatment of recalcitrant lateral epicondylitis. Methods From September 2014 to June2016, a total of 15 patients with recalcitrant lateral epicondylitis received ultrasound-guided injection of autologous PRP therapy, including via left arm injection（n=2） and via right arm injection（n=13）. By using twice centrifugal method, the patient＇s own venous whole blood was centrifuged to obtain PRP. All patients underwent PRP injection once a week, a total of 3 treatments were performed for each patient. Results After the first injection of PRP, the patients were followed up for 12 months. One month after the treatment, visual analogue scale（VAS） score was obviously improved, at 3 months after the treatment the improvement of VAS score reached its peak and it remained at this level until 12 months after the treatment. The elbow joint function, which was evaluated with modified MAYO elbow score, was also significantly improved in one month after the treatment, and the clinical effect was sustained to 12 months after the treatment. Conclusion Ultrasound-guided precise injection of PRP can effectively improve the pain and the elbow joint function caused by recalcitrant lateral epicondylitis.