提高机体抗肿瘤免疫中药的现代研究

Modern research on traditional Chinese medicine improving anti-tumor immunity of organism

机体免疫功能与肿瘤生长密切相关,人体可以通过不同的免疫途径启动抗肿瘤免疫应答,从而达到抗肿瘤功能。中药有着几千年的发展历史,中药中的许多成分如多糖、皂苷和酮类等能帮助提高肿瘤患者脾脏指数与胸腺指数、增加T细胞与NK细胞数目等达到抗肿瘤的作用,其中大部分中药属于补益类药物,小部分为祛邪类药物,如清热解毒、活血祛瘀及化痰散结类。通过对有关抗肿瘤免疫中药的文献进行综述研究,总结临床常用抗肿瘤中药及其提高机体抗肿瘤免疫机制,为抗肿瘤中药的基础研究及其临床使用提供参考。

The immune function is closely related to tumor growth,and the human body can initiate anti-tumor immune response by different immunization routes to achieve anti-tumor function.Chinese medicine has a history of thousands of years,many traditional Chinese medicine such as polysaccharides,saponins and ketones and so on can improve the spleen index and thymus index and increase the number of T cells and NK cells to anti-tumor,most of which belongs to the traditional Chinese medicine of tonifying drugs,and a small part is evil drugs,such as the medicine of clearing heat and removing toxin,blood-activating and stasis-dispelling,and resolving phlegm and dissipating mass.Through summarizing the literature about anti-tumor immunity Chinese herbal medicine,we summarized the commonly used anti-tumor Chinese medicine and its anti-tumor immunity mechanism,providing reference for the basic research and clinical application of anti-tumor Chinese medicine.