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肺结核患者免疫细胞、炎症因子及凝血功能的变化及意义 被引量:11

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摘要 目的探析肺结核患者免疫细胞、炎症因子及凝血功能的变化及意义。方法选取30例肺结核患者作为分析组,另选择同期健康体检者30例作为对照组,观察两组研究对象免疫细胞、炎症因子、凝血功能表现。结果分析组纤维蛋白原(Fg)、D-二聚体(D-D)、血小板(PLT)水平明显高于对照组,血浆凝血酶时间(TT)明显长于对照组,差异具有统计学意义(P<0.05)。分析组CD3+、CD8+、CD3+/CD8+分别为(63.11±3.25)、(27.59±2.89)、(1.21±0.12)%,对照组CD3+、CD8+、CD3+/CD8+分别为(67.44±3.35)、(24.77±3.10)、(1.68±0.16)%,组间比较差异具有统计学意义(P<0.05)。分析组白介素-2(IL-2)、白介素-10(IL-10)、干扰素-g(IFN-g)分别为(62.62±4.35)、(29.40±2.59)、(122.12±4.79)ng/L,对照组IL-2、IL-10、IFN-g分别为(57.92±4.15)、(21.06±2.23)、(169.80±5.79)ng/L,组间比较差异具有统计学意义(P<0.05)。结论在肺结核患者中,免疫细胞、炎症因子及凝血功能等指标水平存在明显改变,在治疗中可由此对肺结核机制、治疗、预后等进行分析研讨。
作者 张英凤
出处 《中国实用医药》 2018年第8期40-42,共3页 China Practical Medicine
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