神经重症患者缺乏药理营养素导致不利结局的文献综述

A literature review on adverse outcomes resulting from lack of pharmaconutrients in critically-ill neuro- logical patients

药理营养素主要包括常量营养素、微量营养素、肠道微生态制剂和核苷酸，随着一些大规模随机临床试验结果的公布，人们对药理营养素的应用趋于谨慎。神经重症患者其病理生理特点包括了综合ICU内患者的特点和特异的神经损害，因此药理营养素的应用有其独特性，本文对近几年此类研究加以综述。

Pharmaconutrients refer to macronutrients, micronutrients, microecologics, and nucleotides. Informed by large randomized clinical trials, people have become increasingly prudent in using pharmaeonutri- ents. Critically-ill neurological patients are intensive care patients who have neurological impairment, and there- fore command extra caution in using pharmaconutrients. This article reviews the latest studies on the use of phar- maconutrients in this group of patients.