黄连膏直肠灌注治疗老年慢性心力衰竭患者便秘的疗效观察

Efficacy of Huanglian ointment rectal perfusion in elderly patients with chronic heart failure and constipation

目的:观察黄连膏直肠灌注治疗老年慢性心力衰竭患者便秘的临床疗效。方法:老年慢性心力衰竭伴便秘患者80例,随机分为治疗组和对照组,每组40例。治疗组给予黄连膏直肠灌注,对照组口服便通胶囊。治疗前、治疗1周及2周后评价临床疗效、生活质量及便秘症状评分。结果:治疗2周后,治疗组总有效率为92.5%,优于对照组的80.0%(P<0.05)。治疗组治疗1周后与治疗前,对照组治疗1周、2周后与治疗前的排便频度、排便时间、粪便性状、排便困难、下坠感和腹胀的评分,生理、社会心理、担忧和满意度评分及总分均有所改善(P<0.05);治疗组治疗2周后的各项评分与治疗前比较有明显改善(P<0.01);治疗组改善程度均优于同期对照组(P<0.05)。结论:黄连膏直肠灌注治疗老年慢性心力衰竭患者便秘疗效确切,明显改善便秘症状,提高其生活质量,且可行性强,值得临床推广。

Objective：To observe the curative effect of Huanglian ointment rectal perfusion in elderly patients with chronic heart failure and constipation.Methods：Eighty patients with chronic heart failure and constipation were selected in hospital,and 40 patients were divided into treatment group and control group.Treatment group were given Huanglian ointment rectal perfusion,the control group were given Bian tong capsule orally,the clinical curative effect,score of constipation symptoms and quality of life were analyzed before,1 week and 2 weeks after treatment.Results：After 2 weeks of treatment,the total effective rate of treatment group was 92.5%,better than 80.0% of the control group（P〈0.05）.Treatment group before and after 1 week treatment,the control group before and after treatment for 1 week,2 weeks,the scores of defecation frequency,defecation time,defecation shape,defecate difficulty,straining feeling and abdominal distension physiology,social psychology,anxiety and satisfaction and total score improved were improved（P〈0.05）.After 2 weeks of treatment,the scores of the treatment group were significantly improved compared with the treatment group（P〈0.01）.The treatment group was better than the control group 1 week or 2 weeks after treatment（P〈0.05）.Conclusion：Huanglian ointment rectal perfusion in treatment of patients with chronic heart failure and constipation has good effect,improve constipation symptoms and quality of life and the feasibility is strong,worthy of clinical promotion.