EGCG和AcEGCG对细胞氧化应激影响的研究进展

Research advance in effects of EGCG and AcEGCG on oxidative stress in cells

表没食子儿茶素没食子酸酯(EGCG)是茶叶中的主要活性成分,全乙酰化表没食子儿茶素没食子酸酯(AcEGCG)是EGCG的乙酰化衍生物。本文从细胞氧化应激方面综述了2种化合物的药理作用,总结出AcEGCG在抗细胞氧化应激方面的优势,并为其新药研发和作用机制研究提供借鉴。

Epigallocatechin gallate（EGCG） is the main active ingredient in tea,and the total acetylated epigallocatechin gallate（AcEGCG） is an acetylated derivative of EGCG. To provide reference for research on the drug development and action mechanisms of AcEGCG,in this paper we reviewed the pharmacological effects of two compounds from the aspects of oxidative stress,and summarized the advantages of AcEGCG in anti-oxidative ability on cell stress.