摘要
嗜酸性粒细胞及分泌的多种颗粒蛋白与鼻黏腠慢性炎症反应密切相关。深入研究嗜酸性粒细胞有助于寻找缓解鼻黏膜慢性炎症的手段，减少慢性鼻．鼻窦炎伴鼻息肉复发。本文就目前嗜酸性粒细胞的生物学特性及嗜酸性粒细胞与慢性鼻-鼻窦炎伴鼻息肉发病机制研究进展进行综述。
Eosinophils and their secreted granule proteins are associated with chronic inflammatory response in nasal mucosa. Knowing more about eosinophils helps us explore new strategies to alleviate inflammatory response and reduce the recurrence of chronic rhinosinusitis with nasal polyps （CRSwNP）. In this paper, we focus on the new progress about eosinophils and their relationship with pathogenesis of CRSwNP.
作者
栾格
郝蕴
玄丽佳
蓝凤
张罗
Luan Ge, Hao Yun, Xuan Lijia, Lan Feng, Zhang Luo(Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing Institute of Otolaryngology, Key Laboratory of Otolaryngology Head and Neck Surgery（Capital Medical University）, Ministry of Education, Beijing Key Laboratory of Nasal Diseases, Beijing 100730, China ; Department of Allergy, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China)
出处
《国际耳鼻咽喉头颈外科杂志》
2018年第2期98-101,共4页
International Journal of Otolaryngology-Head and Neck Surgery
基金
教育部长江学者和创新团队发展计划（IRT13082）,国家自然科学基金重点项目（81630023）,国家自然科学基金国际合作研究项目（81420108009）和国家自然青年科学基金（81700887）联合资助
